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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 50.6.79.85, North America, US
City: -83.1383 Ohio, United States
Very cool little pen. The video quality is very good and the battery lasts a decent amount of time. It is little bit obvious though the pen is larger than a normal pen and there is a green light that comes on while your recording.
I am in meetings all day long, but i am also a big gym guy, so a product like this seemed to make a lot of sense for me to try. And because I did recieve the product for a discount, it even made more sense to me. This supplement arrived very quickly and was well packaged. I was somewhat skeptical about it at first, but thought, it can't hurt to try it, right? So I tried it. I have been taking it as directed for about week or so now. "Improves memory and brain function." Is a pretty subjective statement and I can't say that it has made any remarkable improvements in that category. I didn't forget to pick my kid up from football practice, true, but as I said- it is hard to evaluate that sort of claim. However- I have had no side effects either - no issues with digestion; no upset stomach or the like. Since dementia runs on both sides of my family I think this pill is worth the small investment to help me to prevent not knowing my friends and family later on. ( although there are some people I would like to forget.) Since it can't hurt, it can only help and it is affordable I am more than happy to continue to use this and I am happy to suggest it to others.