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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 185.86.79.121, Europe, UA
City: 30.5233 , Ukraine
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UAG is the best case out there for me. It is extremely durable, but doesn't add much bulk to the phone. I have dropped my phone probably two dozen times and this case has held up perfectly. A friend of mine uses it as a bottle opener all the time with no ill effects. (I would not recommend doing this! haha)
This set is really nice! It comes beautifully boxed with this wonderful variety of essential oils inside. The oils themselves are nice and potent, and a little goes a long way. It has 6 of the most common used oils - Lavender, Tea Tree, Eucalyptus, Lemongrass, Sweet Orange and Peppermint.
These are working really well. We have a huge problem with mice getting into the camper. Camper is 16 yrs old so it is not built like the ones today. We have a number of open areas under the camper. Plenty of ways for mice to get in. So far these are working really well. I would recommend this product.
I should have read the description much more carefully. This product only has a small amount of Tea Tree Oil, and is mostly other non medicinal oils. The scent is pleasant, and made a nice addition to the skin care products I produce for myself, but I had to go and buy pure tea tree oil elsewhere.
The cover of the sunglasses seems fake. I already own the same glasses. Even the shine of the golden frame is not as good. No authentication certificate with hologram which normally accompanies the ray ban? I am doubtful! Better try & buy from local vendor.