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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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Country: 199.0.184.165, North America, US

City: -97.822 , United States

  • Amazon Customer - Great tea, recommended for anyone who have a hard time going to the bathroom.

    Before I don't like drinking tea at all, but after trying this Nature Ace tea it made me feel fresh and it tasted good.

  • Mark S. Eaton - This product works!!!

    I am a 54 year old bodybuilder who needs more testosterone but does not want to get it from either a patch or roll-on cream. This product, when taken correctly, works and works well. I felt the product working the first night I took it and every subsequent night. Thank you PharmaFreak.

  • Kathleen Polich - Aurora returns

    The story picked up where it had left off in the last book. Aurora was as spunky as ever, and Charlaine Harris supplied the enough twists to keep the suspense going. Hope to see another Aurora book in the future.

  • Michael Friedman - Excellent!

    Wonderful! I read some reviews about a lack of photos, but I don't find that to be the case at all!

  • Amazon Customer - I hate the process of returning something online so I ended ...

    The item didn't work! I hate the process of returning something online so I ended up keeping it. My poor daughter keeps pushing the buttons thinking it would work

  • Ron B. - Great bang for the buck

    This is my second exhaust purchase from Danmoto. I installed this one on my 15 Versys. Great bang for the buck, solid fit and finish, terrific sound. Only problem was that the port for the O2 sensor was to big. I emailed this to Danmoto and they responded right away with an adaptor bushing (actually sent 2). I'm sure they will include these in all future shipments. Again, great product for the money (especially a full system).