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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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I love this backpack! I got it for college, I needed something that was big and had a lot of space but wasn't like I was carrying around a suitcase, and I got what I needed. It has so much space and its a comfortable fit when its really heavy.
The Dorco Pace 6 is probably the best razor I have ever bought. It feels comfortable in my hand and is made out of quality products, not the cheap stuff that is just as expensive.
There is no thread adapter and therfore I can not install this on my 2012 Wrangler. I think the thread size on my wrangler is 5/16 X 18.
Just finished the third in this series, and my last. The characters are well described, so you do care about them, despite the got-to-be annoying banter between Marco and Abby. My disappointment was with the science, or lack of it. The science was the book equivalent of the "Starship Troopers" movies..quite un believable. Propellers on Shuttles, pull cords on cannons on a spaceship. But overall it was good enough to read at least these three books.
Love this mascara! Great coverage and stays on all day. However, the application wand is a little big to me.