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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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  • ck_from_nj - Pricey but worth it

    I bought this for my daughter. At 5' she needed a very light weight bag for walking the course. This bag is very light and has lots of ample storage pockets. Well worth the expense!

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    Maybe it's because I didn't read the details well enough, but I wanted this for a healing piercing, etc. and when it came I realized it's for scalp and nails, etc. I didn't want to risk using it on piercing when it had more than just tea tree oil as the ingredient.

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    It was a disappointment. All the best parts were in the trailers leaving you with no "funny" surprises. To bad, with all these very funny women staring in it I thought for sure it would be a good laugh but not.

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  • Elise Cohen Ho - 10-Day Detox Diet Highly Recommended

    As a Holistic Health Practitioner and Nutrition Coach, I am proud to recommend The Blood Sugar Solution 10-Day Detox Diet to my clients. This is so much more than a weight loss plan, although that is a huge benefit to the program. This plan is about reducing inflammation so that you can live a happy and fulfilled life that is free of pain, constipation, headaches, and sugar addiction.

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    I'm giving this four stars for now. I read all the reviews and decided to dilute this with fractionated coconut oil and apply to my feet at night. Two applications and I can already tell that I'm not continuously looking for food. I tend to stress eat and I've had a very stressful couple of days. No additional snacking, that's a plus so far. I'll update in a while to see if this method helps me lose weight.