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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 46.101.82.109, Europe, GB
City: -0.0955 England, United Kingdom
I grew up very healthy, moved to the United States when I was 16, then I had a deadly allergy attack (acute anaphylaxis) while playing tennis at the age of 23. Immediately following that incident I started experiencing many symptoms from chronic fatigue, bloating, depression, anxiety, joint pain, constipation, diarrhea, acne, asthma, ear infections, sinus infections. After going to an allergist, rheumatologist, gastroenterologist, and 4 other general physicians, all my doctors were clueless as to what why these symptoms were persisting. I eventually discovered that the root cause to all of my "constellation" (as one of my doctors put it) symptoms was the fact that I had a Saccharomyces (beer/bread yeast) infection in my gut along with a sensitivity to dairy (IgG and IgA mediated immune responses). The cure for my maladies: paleo-like or low FODMAP--extremely low carbohydrate and sugar diet--with no dairy along with a mild anti-fungal medication. This was the solution after spending $20,000 on an elimination based diagnostic method. After all this, one day by chance I went to the restroom after my brother and saw his stools were not of a healthy digestive system, looked very similar to how my stools turned after my accident. My brother was going through is first two years after a diagnosis for Schizophrenia and Bipolar disorder. I had to go online trying to put together the very disorganized data about the gut to schizophrenia relationship. And sure enough, after my brother had a similar test like mine, we saw his gut had a few pathogenic parasites, an overgrowth of Candida Albicans, and very high IgG and IgA responses to dairy. After I put him on a paleo like diet the results were amazing. It was an instant improvement, the changes in his mood and cognitive capabilities were more than we could have ever expected. This well-written book has a wealth of information about the importance of gut health from a very credible and passionate medical professional. The 25 page bibliography is a testament to the quality and validity of the book. I love this book, and I just wish everyone were aware about the information inside.
How does the publisher justify charging $16.99 for the Kindle edition and $16.50 for the hardcover edition? Ridiculous.
Christians are, in the main, lacking in information about how the world is speeding towards the events foretold for the End Times. This book is a bit rough to read as it talks about "fearful" things. But it would be wise for Christians to become informed so they will not be deceived or taken unawares.