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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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  • Kathleen Blair - Owen makes history and his story.

    What a great read! I look forward to reading the entire trilogy. Tony Riches shares his research in an increasingly personal first person account of the hardships and great joys endured by Owen Tudor. One of the most enjoyable historical novels I have read. Thank you Tony!

  • Beach Gal - Great shade

    This is a great shade. I live in a sunny climate and have always bought the cheap (under $10) reflective shades, but they are too small for the C-Max. I actually got this from the Ford dealer for a few dollars less, but the model number and manufacturer (Intro-Tech FD-55) are the same as listed here. This is very sturdy and of better quality than any of the other reflective shades I've owned, and it fits perfectly. Hooray! Combined with after-market window tinting, we are much happier campers.

  • -dB- - Great accessory for anyone that has a trail camera!

    Bought for dad to use in the field when he's hunting and wanting to look at what was caught on the trail camera. Works great. He hooks it up to his Galaxy 6 and plugs in his micro sd and viola, trail camera images right on his phone! Highly recommended!

  • Voice of Reason - Total Transformation...of your money, into their pockets...FOREVER!

    For those of you who, like myself, chose to buy this program from Legacy directly, I strongly suggest you check your credit card statements. This company baits you into selecting their "trial" for a support line for initially just $1...but if you don't call and cancel, you'll continue to get charged $49 indefinitely. They don't care if you don't recall requesting the trial option, that you never used it, etc.

  • Matt - Great overview for your Iceland adventure!

    This book was very helpful on my two week driving and hiking adventure in the Summer of 2015. I relied on it as my only professional tour book during the trip. While it dives into deep detail on some locations / topics many entries are smaller summaries of several paragraphs in length. That's not a nit on the book, rather those small summaries provide more than enough context to do a quick Google search for more info if something catches your eye. Just enough detail without being overwhelming.

  • Amazon Customer - Yaaaas!

    I just finished ny first week using this product and Ive lost 5 pounds so far...mind you I am roughly 10-15 pounds overweight. What I like the most about these pills is that in the middle of eating a meal....I'll magically feel full and stop eating. EXERCISING AND EATING HEALTHY is a must. These also make me use the bathroom everyday which is great. They give you an energy boost as well.

  • D. Gonzalez - Hollywood Beauty Tea Tree Oil

    Great product for dry skin. I use it on my face and neck in the winter and you can rub it into your feet.