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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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    Presents a very positive image of dads. This is how all dad should want their kids to see them (whether it's true or not)!

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    I had initially hesitated from purchasing the product because of the price. But, the lady somehow managed to convince me with a free product demo. I suffer from oily and acne prone skin and my skin breaks out quite often as well. I was a bit apprehensive about applying the products on my skin, but when I saw the amount of dead skin it peels off, I start believing in the product. I purchased it and applied it in the coming weeks hoping to get better results. I was surprised when I started getting compliments about my complexion. This was a first for me and I was really pleased.

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    Works as advertised. If you have many bottle make sure you have lots of ice. Is a little messy on start up, but it gets the wine to the right temp every time. Take anywhere from 3 to 6 minutes depending on the temp you want.

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    I always blame myself when I don't 'get' a story. It could be me, but some of these were very odd. I can't really say any of them will stay with me. I always enjoy the reading of them though.