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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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PERFECT fit and INSTANT heat reduction. Summer has been brutal and I didn't want the sun killing our new dash in our Sprinter RV. It worked so well for heat reduction while parked in storage, I think I will use it in lieu of the privacy window wrap that came with the camper! I can;t wait for the side window covers to arrive!
Went to the doctor and this was sitting on the table, so I read it while waiting for my appointment. What mindless drivel. I understand that TimKaine is a Godless Communist hiding behind the facade of a normal politician, but the combination of him & Mrs Clinton is unimaginable. Summed up, they'll do for us what she did for Libya and Syria. More open borders. More unvetted Islamic immigration. More terrorism our streets.
Purchased the antivirus for two computers. Worst decision I have made regarding software. Completely destroyed one PC and brought the blue screen on windows 8. Wasn't able to log in and had to reformat to initial settings. Second PC had no internet connection even after I uninstalled the software. Played with internet settings for over 2 hrs until I restored.