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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Really efficient when training with plyo boxes and ladder drills. My daughter loves using for slide drills. It is definitely worth the investment.
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My new waterpik is wonderful. My old one was dropped and thats the reason for my purchase for a new one. I would recomend this product to anyone. This product can and has restored my teeth and gums. You can't put a price on that.
bought this for my parents who are wanting to make there wills and thought i will use it as well it's never to early to think about this kind of stuff
I usually am not one to pay a lot for headphones because I tend to always get shorts in the cords or lose them. However, I was given the opportunity to use these and I could not be more satisfied. I am planning to purchase another pair as a gift for my nephew because he tends to be just as hard on his headphones as well. The headphones paired with my phone easily. The sound quality is nice and they are very comfortable o wear. They are pretty flexible and allow you to continue your normal activity and lift without the hassle of getting tied up in cords or other problems. The headphones came with a charger and did not take long to charge. I charged them for a couple of hours and was able to get through my entire 8 hour work day with them.
We have an old inside cat who started to urinate inside...We are hoping for a miracle with this product. So far, so good! This seller was much more reasonable than the retail store...and the product was new, sealed in the package.