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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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I just bought it yesterday and was so sadly surprised after opening the jar. It looked GROSS! I had to pierce the upper hard wax layer to reach the cream beneath. I didn't like the texture at all. Its like spreading a bad quality old (kept in open for sometime) toothpaste on your face. And it just sits there with a white cast without getting absorbed. No moisturizing qualities for my dry skin at all. I never used the original formula but this new one is YUCK!
Fitting is very nice. Very perfect. Keeps my new Accord clean. I would highly recommend these mats to anyone who is looking to protect his car.
Sprayed on liberally 2 months ago - have yet to notice an improvement in my streaks in my shingles, but will remain patient as other reviews have indicated it may take up to 6 months to notice the improvement. As I have some left, I will try another treatment in the spring if by that time I still haven't seen an improvement.
Price was right. Very easy to install. Feel secure with it. The only compliant I have is the request to run database at least once a week. Too frequent. Would definitely recommend to anyone looking for internet security at a low cost.
This is the first time I've used a hair mask and absolutely love it! My hair has been breaking really bad the past couple years. I started taking different supplements a few months ago, some helped a little. I tried Argan oil which seemed to help more than the supplements. But this is by far so much better and makes a big difference after only one use. Hair feels and looks better. There is plenty in the container for several more uses. My hair is almost down to my waist and i can probably use it 10 times or more.