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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

MRCP(UK) Preparation in Dhaka | DOAMS - At DOAMS, you receive proper guidance with full audio visual support for MRCP Part 1, Par 2 and Paces by Dr M Osman Gani, MRCP(UK) & MRCGP(INT).

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  • Bill - Great Tax Program

    I am retired and my tax return is simple. I also helped two of my sister in laws do their taxes with this program.

  • Mitch - Left it one for 4x the recommended time without results

    Does not work, didn't seem to get cold enough. Left it one for 4x the recommended time without results. Went in to the dermatologist and got proper liquid nitro applied and wart went away in a week. Just go in to the doctor, pay the $50, be done with it.

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    I've been collecting the ornaments since I was given one as a gift about 15 years ago. And this one is as beautiful as the others. Amazon helped by letting me know when it was available and making it so easy to order.

  • Kairus - The best moisturizer

    I've tried many different brands, some even quite a bit more expensive than Perricone. This Face Finishing cream is by far the best moisturizer I have ever used. There really is a noticeable difference that I can see (at 40, my skin looks better than it has in 15 years: poreless and smooth with a touch of dewey glow on top of the cheekbones) and random people (complete strangers, even younger women!) have commented in the last few months that I have really nice skin (they can't all be just trying to kiss my a**!)

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    I love all Design Essential products. This is the only line that has worked for my natural hair. My hair has grown and it's soft. I love the tingling feeling of the conditioner. Love it!