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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 69.30.245.206, North America, US
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Edit, This thing is total trash. Find something else to use. This dose everything I wanted, however after a few months of use, this did nothing but cause more of an issue. It constantly disconnected from the phone, and would not automatically re-connect when back within range. When out of range would be constantly searching again for the phone (Once again that did not connect once within range anyway) that would drain the battery. I put a new battery in every 2 weeks. Total trash, Keep on looking.
This stuff is amazing!!! I have been taking it every day for over a month and my hair looks healthy and my skin looks better than it has in years . My nails are also growing and strong when the used to be brittle and cracked . Slight after taste but well worth it
Works wonders on a short haired dog! I work as a groomer and as soon as I tried this thing I knew I needed one. De-sheds quickly; undercoat and dead hair roll off like a squeegee. I'm eager to try it on my horses next.
Saw all the great reviews for this so I decided to try it. It made my baby cry more. Didn't work for mine.
Great outlet tester, same as those used by professional home inspectors. Checks standard outlet functions with easy to read light outputs, plus an extra feature this unit has over the basic ones is the GFCI test button for GFCI protected outlets (these are the most common to fail!)