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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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Country: 62.156.209.59, Europe, DE

City: 9.491 , Germany

canonphotos - This speaker box has worked well.

This speaker box has worked well. I bought this for my sons Dodge Ram pickup and it works very good. The box is made of particle board and the screws around the speakers have stripped out occasionally but over all it is worth the money

dgatwood - What were they thinking?

Adobe Photoshop Creative Cloud is *not* an upgrade to Photoshop CS6. It's an entirely different model of software in which you are permanently beholden to Adobe, required to pay on an ongoing basis in order to continue to have the ability to open content that you created—content that you own. I understand why Adobe likes this model—it brings in more money per customer, at least from the customers who haven't already dumped their products in favor of Pixelmator and other competitors—but it's a lose-lose for consumers.

bbmertz - High Quality Replacement Antenna

This is a high quality short antenna for the Mini Countryman made by CravenSpeed which is well known for Mini accessories. It looks good, is easy to install and provides same radio reception as the OEM long antenna.