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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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Country: 31.31.72.21, Europe, CZ

City: 14.4112 , Czechia

  • Adela Soriano - by my favorite Aunt, we all immediately fell in love with ...

    I have been a huge fan of Suzanne White since the '80's! Introduced to her books, by my favorite Aunt, we all immediately fell in love with not only her knowledge and spot on descriptions about our very own signs, but with her hilarious turn of phrase. We actually had Suzanne White parties, where the guests all purchased her books and we sat around drinking wine, eating great food, reading her books and learning more about one another. I have been buying her books for years to help guide me through the various months. And I can say without a doubt I have always found them useful in my every day life. This year's recent publication - 2016 Fire Monkey Year is no exception. Both my husband and I are Taurus, and in reading the description of our 2015 year - which as she states we aced our way through a frantic 2015 - we can hardly wait for 2016! Thank you Suzanne for getting us through. A great book as usual. Please buy. You won't ever be disappointed with Suzanne White!

  • RF=GOAT - Despite great ingredients can't live with the smell

    Was in a rush to buy shampoo for my little one, hence didn't buy it on amazon.com but at a local New Seasons market. I liked the smell from the bottle and quality ingredients used. However, once my baby's head was washed using this and hair had dried up the smell has changed somehow - it smelled like rotten oranges. Even the next day I smelled her hair again and it was the same - just bad smell. Returned the bottle to the store.

  • Kit Cassingham - Easy and Effective

    I used a different product years ago to design our house. Fortunately our builder was able to translate our ideas, as represented by the result of the program, and create floorplans that the engineers could use. We love our house. And now that we are ready to build again we decided to give this a whirl. I love the ease and professional results I get from this program.

  • Tini - SMell pretty good do and It makes it easier for me ...

    This really helps my aching muscles as I am an active lifter. SMell pretty good do and It makes it easier for me to relax instead of having tight muscles. I love the container it comes in as I do with all of Baebody's products. It came wrapped in bubble wrap for saftey which I greatly appreciate. I received this product at a discount for my unbiased review

  • G. Dent - Connectivity issues {Fixed}

    Someone before mentioned issues with the computer remaining connected to wireless. I had the same connection issues, but they were fixed with a driver update (this is a VivoBook X540SA.)

  • Timmy C Huynh - Works perfectly fine and offers the protection and minimalistic look that I ...

    Bought two cases to try and ended up using this one for my own IPhone 6 Plus (pink one was for wife's IPhone 7 plus). Works perfectly fine and offers the protection and minimalistic look that I was looking for.

  • Jason Clemmer - It looked great but fell short when listening to standard AM/FM stations

    It looked great but fell short when listening to standard AM/FM stations. Sirius/XM was fine though.