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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
Gemma's Fitness Journey – www.instagram.com/gemmasfitnessjourney - Fitness motivation, product reviews, healthy meal ideas and anything else I feel like writing about :)
Country: 192.0.78.25, North America, US
City: -122.4156 California, United States
Assembly was easy. The telescope is just as described and has the features I was looking for. Good product for the price.
This is the real deal. I recently bought a smaller tube from CVS, and I loved it so much I got the larger version from here. I read some reviews about this being a potential knock off and how this one is orange tinted instead of pearly white. Well I compared this one to the original Macademia from CVS and they are BOTH slightly orange and pearly tinted. The scent and consistency are the EXACT same in both products. Perhaps a few people actually got knock offs, but I sure didn't, and I'm very happy with my purchase!!
I own this and the preceding 3 editions, always purchased for creative writing class purposes. They are exactly what the title suggests: the best american short stories from that year. There are always a couple of really strange stories, but all are excellently written and manage to entertain as well as teach the reader something about the human condition.
I've used this product for years and still love it. I've always put it in my hair before bedtime but when I got married, my husband couldn't stand the smell full strength, although he loved the smell of my hair after washing it (I also use the Ojon shampoo and conditioner, same scent). I have long, thick, course, wavy hair, which means incredibly frizzy if left to it's own devices and nothing else works like this stuff does. I've tried coconut oil, expensive olive oil, creams, foams, you name it. This stuff is still the best! Now I just put it on before a shower for a few minutes because I won't give this up. Oh, and yes it's overpriced, I completely agree with that, but you have to splurge on something!