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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 52.210.88.232, Europe, IE
City: -6.2595 Leinster, Ireland
I am very happy with the Nomad 7 and the Guide 10. The batteries charge within 2-3 hours in sunlight; it takes longer on cloudy days. The built in LED light on the battery pack is a very good idea. My only complaint is that it does not charge my Motorola W755 cell phone. Overall it is a good product.
Not happy with the design of this product. If I still have the package I would return this organizer. First of all you need to take if off every time you fold up the stroller which is a huge pain. It does not fit tightly across the handle bars, the cup holder is a joke, not sturdy at all. Overall the design of this product is terrible.
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I bought these wrenches to use at work (small engine mechanic) and they have far exceeded my expectations. I've had them well over a year and use them daily. Not a single wrench has broke or been stretched out. I don't know if they're just that good of quality or I got lucky but these have worked out perfectly for me.
I cut a banana with a knife yesterday and I felt so worn out and lethargic. Banana slicing the old fashioned way can really wear a person out. Luckily I have the worlds greatest BFF who knew just what I needed and bought me the slicer! I actually have enough energy now to eat my banana after I slice it! Great friend, must have product!
Works ok, but the end that screws to the monitor is flimsy and can be easily bent up or down while positioning the monitor. Once its in place, it seems to be holding postion. Time will tell.