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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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The color and the texture of this item are really nice. It says it’s a bassinet sheet but just like the picture shows it is rectangular. That doesn’t mean it doesn’t fit my oval bassinet thing because it does very nicely, but it does allow excess in the corners that I'm afraid will be pulled and bunch up when the baby starts to move a whole lot. (I don't know this for a fact but it seems like it would.)
I have been a Norton fan since 2005... before that I was a McAfee fan because Norton products hogged up computer performance and McAfee did not. Well this update takes us back to the bad old days... I should have read the forums outside of amazon before I made the purchase. Norton 2013 slows your PC down to a crawl and has add-on products popping out all over like legs on a spider. Horrible! I took my laptop back to factor with a full formate and reinstall just to get rid of it. Thankfully a friend told me about Microsofts Security Essentials which is a FREE Antivirus/Spyware that knits into your OS like ice melts into water. I have never ran so smoothly... tip: make sure you get all your important updates and if you have a mass of them like I did from doing a full format be sure to install the Windows updates in small chunks of about 10 at a time... its quicker than trying to get all the updates with one massive download and install. BEWARE OF NORTON Antivirus 2013 until they get the performance issues fixed... for better still do a format and reinstall using the FREE Microsoft Security Essentials from Microsoft.