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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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Country: 77.244.254.19, Europe, AT

City: 16.3667 , Austria

  • Laura - Love this shampoo

    Love this shampoo. My dog had unknown flaky patches on his back and belly, after the first use most of them disappeared. I'm washing him with this shampoo twice a week

  • Van Johnson - results

    My hair dresser told me about it. I love the product. Would recommend to many friends with simular hair. Thanks.

  • AnaS. - a must must must

    this is a must-have in any girl's makeup bag. gets rid of those crazy bags and shadows under you eyes. just be careful though bc if you wear it alone, i've noticed that you can see the crease of the paste once it starts to get warm or if you've worn it for a while. remember to put some powder over it. and then layer again with just a dab of the paste.

  • Amazon Customer - Leap Frog Tablet

    I ordered the Leap Frog Tablet for my granddaughter's 4th Birthday. She absolutely loves it. Very educational! She is learning to read and write. She enjoys adding new stories and games.

  • Amazon Customer - Good product

    I liked the products quite a bit, but I felt like the evening tea does more for me then the daytime tea. It did help with bloating and aiding in a better nights sleep. I didn't feel like the daytime tea really gave me any kind of energy boost throughout the day. I may reorder in the future.