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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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My new favorite beauty product by far!! I have extremely soft teeth and have had a lot of dental work done because of it so keeping my teeth white has never been easy but this product has changed my life!! I have only been using for a week (they recommend waiting a month to see results) and I can already see a huge difference!! It was weird at first using a powdered toothpaste and watching my whole mouth turn black but now it's like my favorite part of the day. It is kind of a pain to brush with toothpaste or water again after using this but it is so worth it to have a pretty smile again!! I doesn't really have a taste to it but it is not unpleasant in any way by any means! I highly recommend! I have even got my husband to start using it! This is definitely something I will keep using and tell everyone about! I did receive this product for free for me to review but the is my honest and unbiased opinion and review.
It did nothing, followed instructions to the T and hole remained. Finally found pinhole and used good old patch and poof no more leak....sorry I did not listen to the negative comments and save my money :(
What ever you do don't buy this product. I haven't smoked in 3 weeks and I had to take a drug test. I bought this drink just to be sure that I'll be clean and I still came up positive