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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 54.191.112.5, North America, US
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I studied the specifications of many battery chargers and reviewed their customer feedback on amazon.com before I chose the BatteryMINDer 2012 charger.
This works great! I sealed the small holes in the back and plan to place anything I put inside in a plastic ziplock bag to keep everything dry just in case. Very handy for keys if you are at the beach
I've gone through all 10 days and am now starting the "Adventurous Plan" - one of the plans recommended after the detox. I've read other reviews on here who didn't like the book, and I'd like to point a few things out:
I have been using this stuff for about 10 years now. This is one product that I hope to God never stops being made. Not only does it smell awesome (to me) but it makes my hair feel so soft and smooth. I have very thick hair, and I have colored it as long as I can remember. SO if I left it alone and blow dried it (and that was it), its not overly frizzy but just enough to look like it might be damaged. When I use after party on it, I use it much differently then it says on the directions, I put a half squirt in my hair while its wet then dry it. I know my hair so overly dry and doing this on a normal head of hair might make it look and feel greasy. However its perfect for me. I then flat iron it and it will last and look awesome for three days. After 3 days of not washing it, my hair looks disgusting no matter what product is in it. And when I say looks awesome I mean like Jennifer Aniston's hair awesome. Its shiny and smooth. I do attribute it all to Bed head after party because it never looks awesome when I don't use it.