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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
Mostyn Perspectives Home - Mostyn Perspectives - We are an online magazine dedicated to expressing the perspectives, interests and passions of Steve and Amber Mostyn. Our focus is also to feature the...
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The laptop was everything I was hoping for and more. It got here ahead of time which is a first. The boxing leaved a little to be desired but the laptop had no damage and was pristine. Great low budget laptop.
This product did reduce cellulite within 20 days. I did rub it in for more then the recommended time on the product but it works fast and I barely have any cellulite on my legs now.
I was very disappointed in the quality so much so that I only used it for a week before buying the real deal from Quadratec. I could tell the difference in quality almost immediately. The only reason I didn't give one star is because of the price. Other than that its just another cheap knock off.
This is the most amazing book I've read in a long time. EVERYONE should read every single book she has written NOW!
It is not worth the money. Cheap. The material covers the volume buttons and hard to push causing damage to iPad buttons over the course of a month.