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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
NuvaRing Truth | The real truth about the ring - These are only some of the women who have been harmed or died while using NuvaRing Also click here to check out Updates for interesting news and recent posts We know you are considering NuvaRing because it sounds so easy. Maybe you don't want to be hassled by taking a pill every single day. Maybe you…
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This product is amazing. I purchased it in October from Amazon and registered the warranty right away ("Your 15-Months Limited Warranty has been activated.") recommended it to everyone for months. It does what no blender or food processor can do - liquify and transform any mix of veggies, nuts and water or milk into a delicious elixir. So why a one star review?
I had this burning sensation on my back and shoulders so decided to use this lotion since it claims to be healing. I had terribly itchy skin and had rashes after I used the cream. I used it twice and both times I had the same reaction. It might be good for people with not so sensitive skin but it is not for me.
I've got old asphalt tiles in my basement. I've tried a number of approached to get a gloss on this floor, but to no avail. The floor was looking really dull. First, I vacuumed it exhaustively with my shop vac. Next, I cleaned it thoroughly with a mild floor detergent (by Zepp, I think). Then, I applied the quick shine and was really impressed by the gloss. Make sure you light up the area to avoid missed spots, stroke marks, etc. It dries very quickly and remains "wet looking" afterwards. The stuff reminds me of a 1960's product, "Glo Coat," with its milking color. Lastly, I tried buffing it just to see if I could get the gloss even higher, but it didn't change it at all. I really love this item!