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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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  • mackenzie obrien - It's not in a pill form so I like that aspect of it and I just add it ...

    I'm not pregnant yet but continue to take Premama to prepare my body for pregnancy. It's not in a pill form so I like that aspect of it and I just add it into my water and I can't taste it at all. Once I get pregnant I'm definitely going to try their other products.

  • Grill master - Other than late delivery, screen is close to OEM.

    It was delivered a day later than what was promised. Overall screen quality is excellent though. Touch is spot on and install was smooth. It does not have any instructions, but as others have said, quality of screen is great and touch is no different from OEM. I suggest watching videos on YouTube for instructions. Added glass protection is a bonus. Will have to see how long the quality hold up though.

  • Kristina E. Jansson - Best mashed potatoes!

    These potatoes are my favorite food in my kitchen right now. They are delicious and only 3 ingredients. When I first made them, I followed the directions exactly except I used a whisk to mix the potatoes in (it is such a fine powder, I didn't want it to get clumpy and not mix). At first I thought that they were going to be watery, but then as I stirred - like magic - they became the smoothest potatoes I have ever seen.

  • Rael - Kaplan NCLEX-RN 2012-2013

    The product came in within a few days and allowed me the time to review the different helpful strategies. I am satisfied with this product and It was at an affordable price.