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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
Psycho Drama: Celebrating Japanese Cinema - Established in 2012 as a Japanese movie review blog, Psycho Drama is a now a website community celebrating Japanese movies, drama, anime, and actors.
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I think this Kindle article is funny and further supports the link between babies and badly behaving CEOs. The charts added a nice touch. If you like this humorous comparison, then you will LOVE
I have baby fine hair, and this lift root spray was made for it! Great product to use when my permanent is on it's last leg. Love it.
This stuff works!! Plain and simple! Really cleans the floor and takes out the smell of my little yorkie's strong smelling pee. Also, my granddaughter decided to take colored play dough and rub into my white carpet. I was living in a rental so that made it worse for me. (I like keeping things nice so I get my deposit back! And it's not my house to destroy.) I tried a couple of strong cleaners I had and those bright colors of the play dough just wouldn't come out. My daughter, who is the mom to the granddaughter that did this, wanted to see if this would work. She came back with her bottle of Kids and Pets and WOW, it took it out immediately without a stain. As soon as you poured it on the stain was gone!! I was so impressed I have had it around my house ever since and used it on all kinds of things. But now that I have a dog, I am so glad I have it!! I ran out and tried something else and all it did was cover up the smell with a perfume in it and the smell came back. So I HIGHLY RECOMMEND this product!!!