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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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I have used NW Progesterone cream off and on for 14 years. I find it is the best for me. Other comporable brands just were not as effective w my hot flashes. I use about 1/4 to 1/2 tsp each night before bed. Dr. Lee, MD (now deceased) literally saved me from an hysterectomy at age 50 by listening to his talk on Bioidentical hormones. I had been experiencing what they call severe clotting and heavy bleeding. I began NW Progesterone cream and after about three months of regular nightime use using it according to his direction on his website http://draxe.com/4-dangerous-and-common-vitamin-fillers-you-must-avoid ALL SYMPTOMS were gone. I am now 56 and continue to enjoy the benefits of bioidentical Progesterone cresm. BTW... after my fourth healthy child was born at age 37, I had 3 miscarriages all after the first Trimester. I was on Pregesterone vaginal suppositories during my youngest childs pregnancy. She was born full term, healthy, and weighed 8.4 #. I have used Ntural Progesterone cream ever since. It has kept me bone healthy (literally heals osteoperosis - see Dr. Lee's extensive medical studies) and feeling good. Wonderful stuff.
I have to go with the reviewers who say this is a miracle. It is amazing. Used this on the hardwood floors on our 40 year old house. The area near our french doors were sun faded, the finish warn off, and they oak wood looked practically white in some areas due to the damage. We knew we'd have to eventually refinish them, but I wanted to spiff them up in the mean time. I can't even begin to say how shocked I was when I was using this. The floors look perfect now! The faded and damaged areas flow seamlessly to the rest of the floor - color matches PERFECTLY and you can't even tell that those areas used to be in such bad shape. I followed it up with the Howard Feed & Wax polish, which gave it a very nice glow.