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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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    Board was doa, these things happen even to great companies, I still think evga makes great products I'm actually using the big brother of this board the x99 classified and live it.

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    It's an okay product. I thought my skin would look clearer and that it would help with my blemishes but it doesn't do too much plus it is kinda drying to my skin. I do feel my skin is smoother right after washing but its no miracle wash. I use another product and not feel a loss for replacing this one. Like I said its just okay.

  • Amazon Customer - Restore lifts off deck

    We purchased 5 gallons of Rustoleum Deck Restore in Sept. 2013. Applied as per instructions. We had previously stained our deck a year and a half prior with another product but were unhappy with the color. We power washed and allowed to dry before applying. Did not have any rain for the next couple of weeks. This spring, the paint is lifting in large chunks, a foot or two in length. Even where it has not come off, we can see air under many of the surfaces. Don't know whether to power wash and apply a thined out coating or try to sand the whole deck (actually three decks).

  • Greg Rogers - I have been reading the BASS series since 2010 and usually enjoy about half of the pieces

    One of the most solid offerings in years. I have been reading the BASS series since 2010 and usually enjoy about half of the pieces. The editor said these stories would surprise readers and they almost all surely do! A good mix of styles and topics as well.

  • Books and Boys - It’s an amazing read and one you really must get your hands on.

    I love a good book that throws a plot at me that I wasn’t expecting. So many of the books I review have similar story lines, and it’s refreshing to find one where the author thinks outside the box.

  • Ibrahim Saleh - TrackR are Fraud

    I do not advice anyone to buy this items, I ordered 2 TrackR , and it take the company 8 months to delver it to me. and when i finally received it, one worked and the other would not contact as a second device, any how i try to communicated with them by email as usually and basically they told me I can not return them i have to keep it as souvenirs...... because i paid using amazon account .