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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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So much postive feedback for these! I have had many people stop me while walking in the city to compliment the color of my headphones. The best part is that I have an extra pair incase I lose these ! The sound quality is exactly like the apple headphones and the cord is long enough to for me to fit my phone in the back pocket of my jeans and to walk comfortably with.
Does what it says it does. I purchased for a 2nd home to monitor temperature and power, because I don't have a phone line or wifi. It's extremely easy to set up, and the company is great to work with. Seems like a small company because they actually answer the phone and walk you through any questions you have. I accidentally killed the power to this yesterday and it immediately notified me just as programmed. As I said, it's simple and does what it's supposed to do. What a concept!!
I've been using this product every evening before bed and it works great. I'm close to 60 years old and my heels would dry out and crack. Worse in the winter. I apply this product liberally to my entire foot, rubbing into heals and other dry skin. Now my heels are soft with no signs of dryness or cracks.
Love this stuff for my 55 gallon and 10 gallon tanks. This bottle is gonna last quite a while as you only use one capful for a 50 gallon and only fill it up to the first thread in the cap for a 10 gallon tank. My fish are happy and that makes me happy. :]