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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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  • hhaywoodjr - Roxio Creator nxt

    Do not Buy this Product. I could not get it to work and the customer Assistance is like play chess thru the mail. If you do purchase it use a credit card so you can at least stop payment.

  • anonymous - After a hard workout 5 grams decreases or prevents muscle ...

    After a hard workout 5 grams decreases or prevents muscle soreness. Take it within 30 minutes of the workout if you're a female.

  • Deborah C. Beno - I scoured the internet only to find term like your skin might "purge" after use

    Okay, so I am not implying that this stuff is not the "miracle cream" that everyone else seems to think it is. I just feel that reviews need to be well rounded to actually work. I have used retinoid products for years. I understand the nuances of slight tingling sensations or mild burning or dryness or flakiness. ALL of those would have been welcomed conditions compared to what I got from this cream! I have never had a blemish in my entire life. After one week of this cream, all of the areas where I had been applying the very small amount as directed, broke out in weird looking sores. Gross but no other way to describe them. I scoured the internet only to find term like your skin might "purge" after use. Believe me, this is not purging…this is outright alergic reaction to something. NOT that I am judging this cream for everyone…just giving others who might fall into my category, a heads up. It is worth noting that I have NEVER had an alergic reaction to any product before. I am not sure what this stuff has in it that my skin hates but I do know that you do not want to experience what I have, if you do not have to! Just be careful. I even backed off and stopped using for days because they advise to do that…nevertheless, the day I started again, BOOM…zombie face…just sayin'!

  • Jason H. Jones - If you would have asked me a year ago...

    I purchased the Nest Gen1 back in January of 2013 at Lowes. They had a deal for like $50 off and it was just enough for me to finish waffling and spend the money on it.

  • Amazon Customer - Pleasantly Surprised

    I am a long time Mac user and find the Chromebook and the Chrome OS very usable. Here are my initial thoughts after a couple days...

  • Nick Ricci - How can you go wrong with Sorry??...you CANT!!

    This game was purchased for my middle-school students. Their ages range from 10-17 and they all love it! It is also great for adults as like me, you probably played this as a kid! Great for kids, great for families, pretty much great for everyone! You can NOT go wrong with Sorry!