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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 37.1.192.83, Europe, DE
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Good news: It worked as advertised. OK, maybe we left a can of soda in there a bit longer than instructed to get it really, really cold.
I was losing my hair in clumps every time I washed it. I went to my dermatologist and she has this product in her office and recommended I use it. It worked so well that now I only use it once a year for a two month maintenance upkeep. I noticed after about 12 weeks new growth and that my part was not so "bald" anymore. I would recommend it to anyone. One thing is, you have to keep up with it as the directions say, and don't give up after two months or three because it really kicks in at the third month. I have recommended it to all my friends.
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I was introduced to this product by Natural Hair Bloggers Glam Twinz and I must say, this stuff keeps my hair very hydrated and moisturized. I use it once a week but you have to use it liberally because 8oz is not a lot but it works wonders if you work it into the hair from root to tip without rushing. Allow it to penatrate through the hair for about 7 - 10 minutes and then rinse out. Love it, Hair so soft.