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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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Country: 31.31.72.21, Europe, CZ

City: 14.4112 , Czechia

  • A. Glass - No problems of any kind

    I've had them for a year and can report no damage or problems of any kind, but I never overheat them and followed the instructions when I received them. I'm also careful to use the proper kind of tools with them.

  • Linda 747 - My Hairdresser Noticed

    I have tried many different vitamins to help grow new hair and help the hair I have grow and Brock Beauty Hairfinity Healthy Hair Vitamins have done the best job in accomplishing both. I'm excited about the new hair and with the growth of my hair. I have not been able to get my hair to grow past my shoulders for years. It was down to the middle of my back when I went to have it trimmed. It feels thicker when I put it in a ponytail and I enjoy the feeling of it down my back. The best part was hearing my hairdresser confirm it!!!!

  • sarah - must have for any wavy/curyl haired girl

    It takes some getting used to, no lathering up. But if you have curly or wavy hair it is worth it. When using this product, my wavy hair is actually curly. And I have noticed when using this and the once curl conditioner, I can use my normal curl creme (not a devacurl product) and scrunch when wet and go. It will dry a nice wavy, almost curly beachy look. And if I use my diffuser and actually dry it, it is downright curly. Only draw back is how much of the shampoo you use. I recommend buying a larger quantity bottle of the no poo cleanser and a smaller one curl conditioner. It has worked great for me.