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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 208.43.141.139, North America, US
City: -122.3321 Washington, United States
Seems to provide an accurate reading so far. I also like that it displays different color lights based on the temperature range. Another cool feature is that you can check the temperature of inanimate objects as well. I've tried several different types of thermometers and so far this is the best one we've bought.
This caulk was fantastic. We used it to cover up some moldy/mildew-y stains in the graut cracks in our shower...and it worked brilliantly. The caulk was easy to handle and apply with the squeeze tube. Now it's one year later, and the places where we applied the caulk still look brand new. Really impressed by this stuff!
So cute and soft! I love how the ears stick out of the hat. I wish there was a "2014" stitched on one of his paws or something. I checked out 2012 and 2013's bears and they are both adorable as well...with a baby on the way I'm sure I will be buying toys up the wazoo going forward, might have to start collecting these each year!
Great rock star romance book. This story drew me in from chapter 1. I loved Kaz and Lara's story. It was full of all the good feels....angst, heartache, anger, fear, and most importantly love. It is an excellent story to prove that good things come to those that wait for the right time. I loved Kaz's quiet sexiness. He was the entire package for me and such an amazing book boyfriend! I loved Lara and the fight she had within her. The issues she is going through in the book will leave you heartbroken for her, but fighting for her courage to stand up for herself. I loved her character and how she developed throughout the book. This book can be read as a standalone, but the entire series is wonderful. It was great to have the band back together and get a glimpse into all their lives again.
Amazing product ! It's always wonderful to see how technology has advanced to create amazing products . Highly recommended to anyone who wants to upgrade there old car stereo to include blue tooth streaming from their smart phone including music and phone calls !