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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
Carryduff Surgery - Information about the doctors surgery opening hours, appointments, online prescriptions, health information and much more - Carryduff Surgery Carryduff Surgery,Hillsborough Road,Carryduff,Co Down BT8 8HR, Information about the doctors surgery opening hours, appointments, online prescriptions, health information and much more
Country: 94.236.93.178, Europe, GB
City: -0.1224 , United Kingdom
It works great!!! I used it on my antique kitchen table that gets a lot of daily wear and tear. My girls are always spilling milk, water, water colors, etc. The table had faded and this brought it back to life. It was quick and easy to use. I love this product!
We were going to World's and Ocena's of Fun. I got these so we didn't have to worry about phones getting wet and didn't have to worry as much about them getting lost. They were great, my phone was under water several times and didn't get any water on it at all. I could take pictures with it inside the bag. We kept getting asked where we got them. I think people were hoping the park was selling them. That would be a great idea actually. You can talk and text too but texting is more of a challenge and sometimes it's hard to understand people when talking.