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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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Dominique Jones - Great Book..

Great buy helped for my NCLEX-PN prep.. I passed my test and have been working as a nurse for a few months.. :)

Lynn R. Baker - Just like other posts I have read

"Just what the Dr. ordered". There are two tabs you have to remove on the top to make it fit a Ranger pickup. Just like other posts I have read. I used all the brackets for my radio except the front bezel.

garo - Seems pretty good after I put an SSD in it

Seems pretty good after I put an SSD in it....you know it's time that all laptops have SSD's as standard.....please no more 5400 rpm HD's!! Also upon removing the MB to install more memory I found no expansion slot...just 4gb of RAM soddered to the board. So it's limited to 4gb RAM. If anyone sees different please let me know. All-in-all can't complain for the price.