www.drdavidmalouf.com.au Review:

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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

David Malouf | Urological Surgeon based in Sydney Australia Dr David Malouf | Sydney urological surgeon - Dr David Malouf is a urological surgeon specialising in uro-oncology, brachytherapy for prostate cancer, erectile dysfunction and urinary tract calculi.

  • http://www.drdavidmalouf.com.au/about/ About Urological Surgeon Dr David Malouf Dr David Malouf - Treatment of prostate, kidney, testicular and bladder cancers, incontinence, erectile dysfunction, kidney stones, benign prostatic hyperplasia & infertility

    Country: 27.121.64.45, Oceania, AU

    City: 143.2104 , Australia

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