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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 68.71.82.159, North America, US
City: -104.9847 Colorado, United States
This kit is great, saves a lot of time with clean up and the holes are cut smooth. Definitely beats cutting holes all day with a jab saw!!
Nice heavy quality and good fit around fender. Removed four screws form front fender. 4 predrilled holes in flaps. Should have been a piece of cake except all holes in flap didn't line up with fender holes. Maybe my truck. Simple matter to drill new hole in flap but knew that if I did I couldn't return them. Drilled hole and I like them. Rears fit the two existing holes but top of mat held by double sided tape. Tape is not the answer. Recommended drilling new hole in fender and install with screw provided. Leased truck so didn't drill hole. Seems sturdy enough with two screws. They look good installed.
This stuff is over rated. I forgot until I received that I had this in the past. It's not had it just isn't all it is said to be. It does leave streaks on my windows. Better with water, small amount of vinger and a squeegee. Yes more work but if it needs to be perfect, that is what works
after laughing at all the harsh chemicals they had become immune to, this diatomaceous earth physically ripped to shreds the evil beings brought into my apartment building when "undesirable" neighbors in. After I killed the bugs, I bought a house so I never ever ever have to go through that horror again!!! When my house got invaded my carpenter ants that similarly laughed diabolically at chemicals, I busted out the leftover diatomaceous earth I had dragged over with me- saved my sanity & the investment on my house! Forget about expensive exterminators with chemicals that don't work- Terminix did nothing for me but take my money- GET THIS DIATOMACEOUS EARTH!!!!
I love the smell, I dont like washing my hair more than 3 times a week and the smell definetly stays, After i wash it, i feel my hair dry, so I would not recomend it if you have very procesed hair... other than that... the product is great, and the sellers deliver on time..
I've had the phone for one year. It was ok, but recently I updated the phone to Android 4.1.1 (I got the update from blu support) and since then the phone is running at max memory capacity, no RAM left for applications. I open an application and it just goes away, the operating system closes it. Blu support wants me to ship the phone to them to re install the original operating system and charges $25.