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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Here's the part of the instructions I should have read first: "NeverWet is a durable superhydrophobic surface treatment. After curing, NeverWet will repel water, mud, ice and other liquids. Cleaning of treated services should be performed using low pressure water spray from a typical garden hose. Surfaces will demonstrate self cleaning properties and will remain completely dry. Treated surfaces should never be scrubbed with brushes or abrasive cleaners. Treated surfaces will lose superhydrophobic properties if exposed to detergents, soap, oil, solvents or high pressure water. Due to the oils in the skin, excessive handling with bare hands of treated materials can cause a reduction in performance. Abrasion will also cause a reduction in performance."
The laptop was everything I was hoping for and more. It got here ahead of time which is a first. The boxing leaved a little to be desired but the laptop had no damage and was pristine. Great low budget laptop.
This replaced a 10-year old plasma, which I thought was still a good picture. I found this on sale, then checked a leading consumer magazine and purchased. Unbelievable quality for the money. Also, the streaming is just as fast as Roku or Apple TV. I just purchased a second one. Oh and another thing, the remote is user friendly. Well planned and laid out.