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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 104.31.85.199, North America, US
City: -122.3933 California, United States
This scrub is very refreshing and is very gentle on your skin. It removes dead skin, dirt and unwanted oils from your face. I love using this and I also use it once a month on my legs too to get a closer cleaner shave. I definitely would recommend this for those who are looking for a refreshing scrub/face-wash. It even smells good!
Have been a Norton fan for about ten years now and will continue to follow in this path. One thing to remember is one product does not fix everything.
I decided to try this out on a bathroom counter that my teen daughter uses everyday as her launching pad. I figure if it holds up under HER use, it'll hold up to just about anything. So far, it looks as great as the day I finished applying the product. In fact, it looks so great that my clients (I have a home salon) didn't even realize that I just re-did our existing counter and didn't purchase an expensive piece of granite. I'm VERY happy with it! The instructions were easy to understand, the DVD was very helpful, and it was fun/easy to do. Our counter is about 3 feet wide and I have enough product left to do our other bathroom and about 1/2 of my kitchen counters (I have a huge kitchen), so for about $70 it's definitely worth the money. The only "con" I can think of is the fact that you have to be careful with anything hot. It says in the instructions to put a hot pad under the coffee pot. In my case, it's having my daughter keep the curling iron off the counter, which hasn't been too much of an issue, just a matter of getting used to doing something differently. But if it would be an issue for you, it would be better to go another route. All in all I'm extremely happy to have a beautiful and economical solution to our ugly '70's counter tops.
I'm writing my first review on Amazon about this product - even though I've been a member of this site for years. This is how unhappy I am with this product and the accompanying service/support. The TV was delivered to my house, and plugged into the wall. The box and packaging was not left behind. At first, I was able to connect the TV to my cable box on HDMI1, and it worked fine. However, as soon as I hooked it up to my blu-ray player on HDMI 2 and then HDMI 3, my experience went downhill in a hurry. The signal from the blu ray player would cut out every 2-3 seconds to a black screen, and then back to the player (as though the disk was playing through).