Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
Mid Sussex Health Care - Information about the doctors surgery opening hours, appointments, online prescriptions, health information and much more - Mid Sussex Health Care Ditchling Health Centre,Mid Sussex Health Care,Lewes Road, ,Ditchling,East Sussex BN6 8TT, Information about the doctors surgery opening hours, appointments, online prescriptions, health information and much more
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Carlos G. Aguilar Trejo - One of my favorites!Hey amigos! I'm veeeeeery happy with this device :) Very good price, excellent size, very good sound and I like the color a lot.
YsOneMN - AS goes the way with Microsoft... now ...AS goes the way with Microsoft... now have to pay for foreign language packs and they are trying to CLOUD BASE as many aspects as possible.
Dr. H - BombedAFTER SEVERAL ATTEMPTS TO INSTALL THIS ON A MAC PRO SYSTEM 10.7.5 I GAVE UP. It wouldn't install. Piece of junk.