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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

Home | NorCal Dermatology | Medical, Surgical, Cosmetic | California - The dermatologists and staff at NorCal Dermatology in Santa Rosa and Ukiah, CA are committed to providing you with the very best comprehensive skin care in Northern California.

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http://www.norcal-dermatology.com/pigmentation.html Pigmentation | Cosmetic | NorCal Dermatology | California - If dark spots are clouding your complexion, call NorCal Dermatology in Ukiah, CA today to schedule a consultation and start seeing clear skin in your future using RevLite laser dark spot removal.

http://www.norcal-dermatology.com/vascular.html Vascular | Cosmetic | NorCal Dermatology | California - Call NorCal Dermatology in Ukiah, CA today to schedule a consultation and treat vascular conditions with noninvasive vascular treatments using the Icon Aesthetic laser system.

http://www.norcal-dermatology.com/gallery.html Before & After Treatment Gallery | NorCal Dermatology | Medical, Surgical, Cosmetic | California - Explore the before and after treatment gallery at NorCal Dermatology and Cosmetic in Santa Rosa and Ukiah, California.

http://www.norcal-dermatology.com/education---resources.html Education & Resources | NorCal Dermatology | Medical, Surgical, Cosmetic | California - For your convenience, we've supplied links to explore if you would like to learn more about your skin conditions, sun protection, and skin cancers.

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