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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

Nurses.com: News and Events for the Nursing Industry - Resource for professionals in the nursing industry- Information on licensed practical nurses, hospitals, patient care, surgery, ambulatory, registered nurses and more

  • http://www.nurses.com/doc/report-highlights-the-future-of-nursing-it-leaders-0001 Report Highlights The Future Of Nursing IT Leaders - CNIOs help bridge the gap between nursing and technology. By Christine Kern, contributing writer
  • http://www.nurses.com/doc/nurse-managed-clinic-leverages-telehealth-to-expand-virtual-health-access-0001 Nurse-Managed Clinic Leverages Telehealth To Expand Virtual Health Access - National University collaborates with Health Net Connect and iAssay to improve healthcare access. By Christine Kern, contributing writer
  • http://www.nurses.com/doc/survey-reveals-how-well-respondents-understand-hip-0001 Survey Reveals How Well Respondents Understand HIP - Results show that just 40 percent were aware of planned Phase 2 HIPAA audits. By Christine Kern, contributing writer
  • http://www.nurses.com/doc/institute-for-patient-safety-takes-aim-at-reducing-medical-error-0001 Institute For Patient Safety Takes Aim At Reducing Medical Error - Collaborative institute to focus on patient safety issues and preventable medical errors. By Christine Kern, contributing writer
  • http://www.nurses.com/doc/quiz-your-staff-with-mobile-apps-0001 Quiz Your Staff With Mobile Apps - Gamification is making learning new protocols easier according to experts who use mobile quizzes to increase information retention among hospital...
  • http://www.nurses.com/doc/the-rise-of-the-cnio-0001 The Rise Of The CNIO - Informatics nurses provide demonstrated high degree of impact on quality of care. By Christine Kern, contributing writer
  • http://www.nurses.com/doc/wallethub-publishes-s-best-worst-states-nurses-0001 WalletHub Publishes 2016’s Best Worst States For Nurses - Washington, Illinois top the list; Hawaii, Louisiana, and D.C. bring up the rear. By Christine Kern, contributing writer
  • http://www.nurses.com/doc/the-impact-of-electronic-health-record-in-nursing-0001 The Impact Of Electronic Health Record In Nursing - The adoption of digital medical record technology has improved the provision of healthcare services substantially. This includes lowering chances of...
  • http://www.nurses.com/doc/from-scrubbing-in-to-geeking-out-how-my-career-took-an-unexpected-turn-to-it-0001 From Scrubbing In To Geeking Out How My Career Took An Unexpected Turn To IT - When you think of nurses working in a hospital, you probably imagine them passing out medications, administering treatments, interpreting...
  • http://www.nurses.com/doc/tomorrow-s-nurse-0001 Nursing A Changing Job Climate - Thanks to new medical breakthroughs, life expectancy is on the rise. From 2010 to 2050, officials expect a whopping 351 percent increase in the...
  • http://www.nurses.com/doc/how-nurses-save-lives-with-preventative-services-0001 Nurses Play Crucial Role In Preventative Health Services - Americans could save billions of dollars annually in health care costs per year if they would follow preventative health care practices. Nurses place ...
  • http://www.nurses.com/doc/why-nurses-are-essential-to-delivering-cost-effective-care-0001 The Vital Role Of Nurses In The Delivery Of Affordable Care - The US healthcare sector will employ 3.2 million nurses by 2022. Presently, 6% of nurses care for one patient, whereas 11% care for three patients.
  • http://www.nurses.com/doc/steps-to-take-following-a-needlestick-0001 5 Steps To Take Following A Needlestick - According to The Centers for Disease Control and Prevention (CDC), nearly 385,000 sharps-related injuries occur annually in the U.S. healthcare...
  • http://www.nurses.com/doc/how-tetris-can-transform-healthcare-operations-0001 How Tetris Can Transform Healthcare Operations - Healthcare providers face an operational paradox — scarce resources are both overbooked and underutilized at the same time. The result? Long...
  • http://www.nurses.com/doc/keys-to-building-a-fortified-staffing-process-ahead-of-the-nurse-retirement-surge-0001 Keys To Building A Fortified Staffing Process Ahead Of The Nurse Retirement Surge - AMN Healthcare recently released its 2015 Survey of Registered Nurses. This research included input from nearly 9,000 RNs on topics ranging from...
  • http://www.nurses.com/doc/the-need-for-eldercare-technology-0001 The Need for Eldercare Technology - Eldercare is not a particularly sexy branch of the healthcare world, but it’s increasingly becoming more important. The senior population in...
  • http://www.nurses.com/doc/top-best-practices-for-secure-messaging-0001 Top 8 Best Practices For Secure Messaging - There’s a reason text messaging is quickly becoming common in the work- place: It’s quick; it’s to the point; it saves time. But...
  • http://www.nurses.com/doc/myanmar-s-delegation-of-medical-professors-collaboration-in-nursing-education-0001 Myanmar’s Delegation Of Medical Professors Visits NCKU For Collaboration In Nursing Education - Prof. Myat Thandar, Rector of University of Nursing, Yangon, Myanmar, led a delegation to visit National Cheng Kung University (NCKU), Tainan,...
  • http://www.nurses.com/doc/press-ganey-launches-new-nursing-performance-solution-0001 Press Ganey Launches New Nursing Performance Solution - Press Ganey Holdings, Inc. recently announced the introduction of its proprietary Nursing Performance Solution, an analytics tool designed to provide ...
  • http://www.nurses.com/doc/ezpbj-launches-experts-network-payroll-based-journal-compliance-0001 ezPBJ Launches Experts Network To Help Skilled Nursing Facilities With Payroll Based Journal Compliance - ezPBJ has established a network of expert partners in Payroll Based Journal rules to help skilled nursing facilities comply with the Centers for...
  • http://www.nurses.com/doc/california-state-university-create-new-advanced-nursing-education-programs-0001 California State University San Marcos Receives Grant To Create New Advanced Nursing Education Programs - California State University San Marcos (CSUSM) School of Nursing recently received a grant from the U.S. Health Resources and Services Administration ...
  • http://www.nurses.com/doc/pennsylvania-department-releases-nursing-home-quality-improvement-0001 Pennsylvania Department Of Health Releases Nursing Home Quality Improvement - Pennsylvania Department of Health Secretary Dr. Karen Murphytoday released the recommendations of the Nursing Home Quality Improvement Task...
  • http://www.nurses.com/doc/rasmussen-college-launches-accelerated-entrance-nursing-degree-minnesota-0001 Rasmussen College Launches Accelerated Entrance Options For Bachelor Of Science In Nursing Degree In Minnesota - Rasmussen College, a regionally accredited private college, today announced the launch of two accelerated entrance options for the Bachelor of...
  • http://www.nurses.com/doc/board-certification-emergency-nursing-honors-angel-medflight-award-0001 Board Of Certification For Emergency Nursing Honors Angel MedFlight With Award - The Board of Certification for Emergency Nursing (BCEN) selected Angel MedFlight Worldwide Air Ambulance as the winner of the 2016 BCEN Honorary...
  • http://www.nurses.com/doc/new-community-health-simulation-available-nurse-educators-0001 New Community Health Simulation Available For Nurse Educators - Healthcare Learning Innovations announces the launch of Sentinel City™ Community Health Simulation 2.3 for the community and public health...

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