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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

North Valley Medical Association » North Valley Medical Association - North Valley Medical Association. Physicians bridging Northern Californians to better health and located in Redding, California - Shasta County

  • http://www.nvma.us/news North Valley Medical Association » News - $12 Million Reasons to be an NVMA / CMA Member, CMA applauds Gov. Jerry Brown for signing a sweeping series of tobacco bills., Vaccines and Senate Bill 277 - Fact vs. myth, CMA creates new resource summarizing Medicare incentive and penalty programs, How to dispute incorrect Sunshine Act data before it goes public, Medical board urges physicians to use online license renewal for fastest processing, California among six states that pay the least for Medicaid beneficiaries, CMA files brief in case that could undermine MICRA's definition, Physicians can review Sunshine Act data starting July 14, 2014, Free webinar: Meaningful use public health measures, Blue Shield breach affects California Doctors, Are your controlled substance prescription pads up-to-date?, Covered CA Outreach and Education for Providers
  • http://www.nvma.us/news/2016/05/cma-applauds-gov-jerry-brown-for-signing-a-sweeping-series-of-tobacco-bills North Valley Medical Association » CMA applauds Gov. Jerry Brown for signing a sweeping series of tobacco bills. | News - CMA applauds Governor Jerry Brown for siging a sweeping series of tobacco bills. 
  • http://www.nvma.us/news/2015/01/cma-creates-new-resource-summarizing-medicare-incentive-and-penalty-programs North Valley Medical Association » CMA creates new resource summarizing Medicare incentive and penalty programs | News - CMA creates new resource summarizing Medicare incentive and penalty programsOver the past few years, Congress has created a number of programs that call for payment incentives and reductions (referred to as “adjustments” by the Centers for Medicare and Medicaid Services) that impact physicians and their practices. At their inception, most of these programs offered an incentive to participate. However, most of the programs are entering their penalty phases, with complex and potentially conflicting requirements and implementation processes.To help physicians understand how these programs will affect their practices, the California Medical Association (CMA) has created a new resource, “Medicare Incentive and Penalty Programs: What physicians need to know.” The resource is available free to CMA members in the resource library at http://www.cmanet.org/resource-library.

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