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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

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Tammy Harvey - Smells great as well as works great

I have short hair and I use this taffy to keep it together. I absolutely love the way this taffy smells. The first time I experienced this product was at my salon. My hair dresser used it and I loved how smooth it made the spikes in my hair without making it stiff or feel goopy. The product is light enough that I can manipulate my hair throughout the day. I also love that it doesn't dry my hair out like other products would if you are trying to have that messy look.

Jordan Barksdale - Out of sight, out of mind!!!

Works great! Easy to install! Now I don't have to stare at that long factory antenna every time I get in my Jeep!