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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
Park Surgery - Information about the doctors surgery opening hours, appointments, online prescriptions, health information and much more - Park Surgery Park Surgery,Albion Way, Horsham,West Sussex RH12 1BG, Information about the doctors surgery opening hours, appointments, online prescriptions, health information and much more
Country: 94.236.93.178, Europe, GB
City: -0.1224 , United Kingdom
A couple of months ago, I noticed I was getting awful radio reception. Turns out that someone had stolen the antenna off my MINI. I got pricing on an OEM one, but I decided to get the stubby instead for a couple of reasons - Prime shipping to my house (i.e., no need to pay for shipping or drive to the MINI dealer), no more expensive, and looked cooler. It arrived as advertised, and I was surprised to feel the weight of it - it's a solid piece of metal. Well manufactured, it installed in about 30 seconds, and I have super reception now. Thanks CravenSpeed!
I would give the Bissell Steam & Sweep 1 star for sweeping, 1 star for performing both tasks together and 4 or 4.5 stars for steaming. I had read many reviews, so was not expecting to be able to sweep and steam together, but I was kind of surprised to see the enclosed directions even say "for best results" to sweep the floor before steaming. It seems to me if you know your product doesn't really work as advertised, perhaps you should change your advertisements.