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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

Home::Global Pharmaceutical Technology :: A leading B2B, Media Portal for Pharmaceutical Industry. - Pharma Tech Global, published by JMC IT Mahal, is the leading pharma title in Online/Print and digital versions serving the information needs of key executives from the world's leading pharmaceutical companies. The magazine covers important Issues and Trends, News, Press Releases shaping the future of the pharmaceutical industry across the world.

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  • http://www.pharmatechglobal.net/knowledge-share/news/synaffix-enters-into-a-commercial-license-agreement-with-adc-therapeutics.php Synaffix Enters into a Commercial License Agreement with ADC Therapeutics::Global Pharmaceutical Technology :: A leading B2B, Media Portal for Pharmaceutical Industry. - Synaffix BV announced today it has entered into a Commercial License Agreement with ADC Therapeutics for its proprietary GlycoConnect� and HydraSpace� site-specific antibody-drug conjugate technologies.
  • http://www.pharmatechglobal.net/knowledge-share/press-releases/siga-announces-commencement-of-rights-offering.php SIGA Announces Commencement of Rights Offering::Global Pharmaceutical Technology :: A leading B2B, Media Portal for Pharmaceutical Industry. - The Rights Offering is expected to expire at 5:00 pm, New York City time, on November 8, 2016, subject to early termination or extension. Subscription rights that are not exercised prior to the expiration date will expire and have no value.
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  • http://www.pharmatechglobal.net/knowledge-share/research-insight/vector-vitale-announces-new-paradigm-in-medicine.php Vector Vitale Announces New Paradigm in Medicine::Global Pharmaceutical Technology :: A leading B2B, Media Portal for Pharmaceutical Industry. - Researchers from Vector Vitale Inc., a Florida (USA) based company, have found that maintaining the right isotope ratio of essential chemical elements representing less than one percent of human body mass is a matter of life and death. Important discoveries allow to understand why and how pathologies are born.
  • http://www.pharmatechglobal.net/knowledge-share/research-insight/global-biobanking-market-2016-2020-analysis.php Global Biobanking Market 2016-2020 - Analysis::Global Pharmaceutical Technology :: A leading B2B, Media Portal for Pharmaceutical Industry. - The market research analyst predicts the global biobanking market to grow steadily at a CAGR of approximately 8% during the forecast period.

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  • Magdalena - Boost of energy

    I am not a morning person and so this mild but effective stimulant is a good kickstart in the am and even when I have a cup of coffee it's not overwhelming. Worth the buy.

  • Navdeep - a bit heavy and bulky but not too bad. left 3 stars because i tried plugging in ...

    very high capacity charger. a bit heavy and bulky but not too bad. left 3 stars because i tried plugging in a micro usb cable to charge the battery and it got stuck. this happened with every cable i tried and eventually it pulled out the insides of the charger when i was trying to disconnect the charger