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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 78.46.43.200, Europe, DE
City: 11.0683 Bavaria, Germany
I'm giving this 2 stars because it made my skin incredibly soft but it also gave me cystic acne on my face. Very painful acne and so many of them appeared underneath my skin once I started using this product. I started developing one everyday, so I've stopped using it. My face is clearing up now. It's just not for everyone. I'm glad I bought the smaller count bottle to try, so not that much of my money was wasted.
This thing is simply amazing. I wish I had had one of these a long time ago. It does just exactly what it says it does, and it really makes building things a lot simpler. This is a must buy for any wood worker, beginner or expert.
Seems like a quality product. I've only been taking it for a few days but I can feel the difference. It helps me feel more awake and alert. Also seems to help with headaches which I get often but haven't had any since I started taking this. I would recommend it.
When I saw Fenix came out with this light using a neutral tint LED, I knew I had to have it! My first LED torch with a neutral tint arrived a few weeks ago, and since then I was hooked. The Fenix PD32UE is just as nice with a perfect tint to show colors properly. This is especially useful outdoors - grass, snow and other objects are no longer blue!