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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 199.0.184.115, North America, US
City: -97.822 , United States
A very elegant pen which compliments the Waterman Ballpoint pen that was passed on to me from my father. Smooth writing rollerball and the heft feels nice in the hand.
Downloaded great. Still have to take tutorial, but am excited to learn the software. With 2 kids in elementary school, knew I needed Publisher, so am excited to learn how to use it!
I like this compacted microfiber towel is light weight, use little space in my backpack, super absorbs the water that needs, have a quick drying easy to travel.
I've been a customer of Organo Gold Gourmet Black Coffee over 2 years now!!! It keeps me healthy, fewer colds...and it keeps my blood going!!
QuickBook 2013 is breeze to use. It was easy to install and the transition was smooth. I would definitely recommend this software to any small business.
Both my daugther and I love this cream. My daugther has super sensitive skin, and we have been spending a fortune on special Clinique products (Redness Solutions series) since that was the only thing her skin would tolerate. Then we stumbled upon the Sebamed products and have used them ever since. Will recommend highly both for quality and price.
Mine arrived different than advertised. They're advertised as having a tab piece attached to the buds that are meant to hold the buds in the ear, but the ones I received do not have the attached piece.. not sure if I'm missing something or what? Otherwise they work okay. Not the longest battery life compared to other buds available on amazon, but they charge super quick.