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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.
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Country: 67.221.190.150, North America, US
City: -73.9979 New York, United States
I don't put a lot of faith in beauty products (if only there was a facelift in a jar!) but I've been hoping for an effective way to remove facial hair that would not require paying for laser treatments. I tried this product on my upper lip about two weeks ago and was delighted with the results.
I can't say enough about this Ninja Pro Blender. I really like the lock on lid, and I also like the way the blender locks onto the base. I have blended Kale, parsley, apples, lemons, spinach, etc. as well as ice and berries. Yes it does leave little "bits" in the juice but it is not a juicer, it is a blender. I like pulp, so I have no problem with the bits. The blades slide off and on easily. The blender is so easy to clean that handling the blades should not be a problem. If you fill the blender almost to the top and add a little soap, pulse a few times, drain through the spout, add water to rinse, pulse and pour, out you should have no problems with the blades. There is also quite a bit of "stem" to the blade section which makes it easy to handle. The only thing that would make this blender more perfect would be if it handled hot liquids. I didn't think that was a big issue but I made a receipe recently that said to blend the gravy bits and I couldn't do it until the gravy cooled. I am very enthusiastic about this blender. It was delivered promptly and is so easy to use. The lid can suction to the blender rather tightly but a little patience and it comes off. I like that kind of security to the lid. I have not dealt with customer service so I can't give a review on that.
First of all, let me say that I've been really happy with this purchase. I bought this treadmill at the end of January / early February, and have had it a little under 2 months. I use it roughly 5 times a week for at least 60 minutes... so far, it's been going strong. My runs range anywhere from a quick walk (3.5 mph) to around 8 mph... and it doesn't seem to have any trouble keeping up. I'm a tall guy, currently 236 pounds, but I was 257 when I began using it... it seems to be able to handle me fine.