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Le fluconazole, commercialisé sous le nom de Diflucan, est un antifongique appartenant à la classe des triazolés. Son action repose sur l’inhibition de la 14α-déméthylase dépendante du cytochrome P450, empêchant la conversion du lanostérol en ergostérol, composant essentiel de la membrane fongique. Cette inhibition fragilise la membrane et conduit à la mort cellulaire. La biodisponibilité du fluconazole est élevée (90 %), avec une pénétration efficace dans le liquide céphalorachidien, ce qui justifie son utilisation dans les méningites cryptococciques. Sa demi-vie longue permet des administrations espacées. Les données cliniques soulignent son rôle dans la prise en charge des candidoses systémiques, des candidémies et des infections opportunistes chez les sujets immunodéprimés. Les références thérapeutiques indiquent que diflucan prix est intégré dans de nombreux protocoles, tout en rappelant la surveillance nécessaire des enzymes hépatiques et les interactions avec les substrats du CYP3A4 et du CYP2C9.

Home | Then Comes Family - A community for every stage of family from TTC, parenting, conception, pregnancy, infertility, miscarriage or loss, childless not by choice, and much more. Then Comes Family provides a space for every family.


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  • Bharat - Best virus protection I've used

    Had Kaspersky for 4 years now (used Norton before) and am never switching. Haven't had any problems and I have teenagers who surf and download stuff daily on their computers and the home network.

  • Tamika Taylor - GREATNESS!!!!!

    I love J. Cole!!! So, when this album came out, I was so excited. What else can be said about this album, but pure greatness. He is the best rapper of our generation. Keep the great music coming, J. Cole!!!

  • Skylamor - Peppermint for Migraines, Tea Tree for Disinfecting Clothing, Kitchens, & Bathrooms, & Much More!

    So, this is a nice group of essential oils to have in your home for a variety of reasons and uses. You get six oils, all in 10 ml. glass bottles with sealed lids. I cant say that I have a favorite because I love them all. For instance, I have used the peppermint oil, just a few drops, on my temples and wrists for migraines and nausea. It takes that edge off and for anyone that has migraines knows how any relief is golden. I use the tea tree oil in the washing machine, takes odors and disinfects the clothing, bedding, towels, etc. The lavender and lemongrass I use in my diffuser for relaxation. I also make home cleaning sprays by using several of these oils alone and in combination in a bottle to disinfect and clean the bathroom and kitchen area. I even spray these into the air to freshen and purify the air. You can add a few drops of your favorite along with water and/ or vinegar. Google ' 'homemade essential oil cleaning' to find your favorite recipes. That's what I did. The homemade sprays are much cheaper than the store bought chemical cleaners and better for our lungs, too! I have had no issues with any of these oils and would purchase again. Price is great for this set. Recommended.